Smashing magazine has compiled an amazingly comprehensive list of tools available to make life easier for web designers.
Handy highlights include
- Ninite - batch installer
- gridr buildrrr - a CSS generating tool
- TitanPad - lets you edit in real time on collaborative text documents
- Divine - a photoshop plug-in to convert psd files to html for WordPress
- Try ruby (in your browser!) - contains a step-by-step tutorial
Read the full list at Smashing magazine.